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Antigenic Specificity | MEKK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, sheep, dog, porcine, monkey, Drosophila, guinea pig, hamster, rabbit, Xenopus |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, dog, Drosophila, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus MEKK3. MEKKs (Mitogen activated protein kinase kinase kinases) are serine-threonine kinases that act as the first tier of cellular MAP kinase pathways by activation of MAP/ERK kinases, or MEKs. Many enzymes with MEKK activity have been identified, including MEKK1-4, Raf, MLK3, TAK, and DLK. MEKKs generally display little similarity outside of their catalytic kinase domains. MEKK1-4 are nearly 50% identical within their catalytic domains, and are known to regulate Erk, Jnk, and p38 MAP kinase pathways. MEKK2 and MEKK3 bind MEK5 via conserved PB1 domains, leading to downstream activation of Erk5. |
Immunogen | Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of mouse MEKK3. |
Other Names | [MAP3K3; MEK kinase 3; MEKK3, pAb], [Map3k3; Map3k3; Mekk3; MAPKKK3; AW548911; mKIAA4031; Mekk3; MEK kinase 3; MEKK 3] |
Gene, Accession # | [MEKK3], Gene ID: 26406, NCBI: Q61084.1, UniProt: Q61084 |
Catalog # | MBS565725 |
Price | $345 |
Order / More Info | MEKK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |