Mouse CD223: Low Endotoxin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD223: Low Endotoxin |
| Clone | [C9B7W] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Flow cytometry (FC/FACS), Functional Assays (FN) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse CD223 antibody, clone C9B7W recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (Workman et al. 2002). |
| Immunogen | Immunogen: Murine CD223 Ig fusion protein Fusion Partners: Cells from immunised Lewis rats were fused with cells of the Sp/20 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; CD_antigen: CD223], [Lag3; Lag3; Ly66; CD223; LAG-3; LAG-3] |
| Gene, Accession # | [CD223], Gene ID: 16768, NCBI: NP_032505.1, UniProt: Q61790 |
| Catalog # | MBS211241 |
| Price | $675 |
| Order / More Info | Mouse CD223: Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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