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Antigenic Specificity | Mouse CD3 |
Clone | [17A2] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3epsilon, delta, gamma and zeta chains. It forms a TCR complex by associating with TCR alpha/beta or gamma/delta chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
Immunogen | n/a |
Other Names | [Mouse CD3; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain; CD3E/D/G/Z; CD3e/d/g/z; CD3E/D/G/Z; CD3] |
Gene, Accession # | [CD3], Gene ID: 12500, NCBI: NP_038515.3, UniProt: P04235 |
Catalog # | MBS2553767 |
Price | $60, $70 |
Order / More Info | Mouse CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Davis MM. 1990. Annu. Rev. Biochem. 59:475. 3. Weiss A, et al. 1994. Cell 76:263. |