DNAJC3 (Center) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | DNAJC3 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mousepredicted: rat |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DNAJC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 189-223 amino acids of human DNAJC3. Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); DnaJ homolog subfamily C member 3; Endoplasmic reticulum DNA J domain-containing protein 6; ER-resident protein ERdj6; ERdj6; Interferon-induced; double-stranded RNA-activated protein kinase inhibitor; Protein kinase inhibitor of 58 kDa; Protein kinase inhibitor p58; DNAJC3; P58IPK; PRKRI] |
| Gene, Accession # | [DNAJC3], Gene ID: 5611, NCBI: NP_006251.1, UniProt: Q13217 |
| Catalog # | MBS9231260 |
| Price | $165, $370 |
| Order / More Info | DNAJC3 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Korth M.J.,et al.Gene 170:181-188(1996). Dunham A.,et al.Nature 428:522-528(2004). Polyak S.J.,et al.J. Biol. Chem. 271:1702-1707(1996). Gale M.J. Jr.,et al.Mol. Cell. Biol. 18:859-871(1998). Melville M.W.,et al.J. Biol. Chem. 274:3797-3803(1999). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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