CASP3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CASP3 |
| Clone | [1E7F9] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2b |
| Format | Protein A purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Casp3 (caspase 3), also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. CASP3 is involved in the cleavage of huntingtin. This antibody can recognize the 32 kDa pro-caspase 3 as well as 17 and 19 kDa cleaved-caspase 3. |
| Immunogen | Immunogen: Fusion Protein of CASP3 Buffer: PBS with 0.1% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
| Other Names | [Apopain; CASP 3; CASP3; Caspase 3; Caspase3; CPP 32; CPP32; CPP32B; Cysteine protease CPP32; Protein Yama; SCA 1; SREBP cleavage activity 1] |
| Gene, Accession # | [CASP3], Gene ID: 836, NCBI: BC016926, UniProt: P42574 |
| Catalog # | MBS2549050 |
| Price | $220, $290, $435 |
| Order / More Info | CASP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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