Phospho-AKT2 (S474) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AKT2 (S474)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis Phospho-AKT2-S474 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S474 of human AKT2. AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Immunogenn/a
Other Names[RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT2]
Gene, Accession #[AKT2], Gene ID: 208, NCBI: NP_001617.1, UniProt: P31751
Catalog #MBS9206389
Price$165, $370
Order / More InfoPhospho-AKT2 (S474) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGeorge, S., et al., Science 304(5675):1325-1328 (2004). Xu, X., et al., Oncol. Rep. 11(1):25-32 (2004). Shim, D., et al., Arch. Biochem. Biophys. 425(2):214-220 (2004). Li, X., et al., Gastroenterology 126(1):122-135 (2004). Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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