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Antigenic Specificity | Dok-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dok-4 Polyclonal Antibody detects endogenous levels of Dok-4 protein. The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive r |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Dok-4 at AA range: 30-110 |
Other Names | [Rabbit Dok-4; DOK4; Docking protein 4; Downstream of tyrosine kinase 4; Insulin receptor substrate 5; IRS-5; IRS5] |
Gene, Accession # | [DOK-4], Gene ID: 55715, NCBI: NP_060580.2, UniProt: Q8TEW6 |
Catalog # | MBS9701905 |
Price | $130, $220, $325 |
Order / More Info | Dok-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |