BBS7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BBS7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: BBS7 antibody detects endogenous levels of BBS7. Function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier v |
| Immunogen | Immunogen: A synthesized peptide derived from human BBS7. Subcellular Location: Cell Projection > Cilium Membrane. Cytoplasm. Localizes to nonmembranous centriolar satellites in the cytoplasm. Tissue Specificity: Isoform 2 is ubiquitously expressed. Isoform 1 is expressed in retina, lung, liver, testis, ovary, prostate, small intestine, liver, brain, heart and pancreas. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Other Names | [Bardet Biedl syndrome 7 protein; Bardet-Biedl syndrome 7; Bardet-Biedl syndrome 7 protein; BBS2 like 1; BBS2 like protein 1; BBS2-like protein 1; BBS2L1; BBS7; BBS7_HUMAN; FLJ10715] |
| Gene, Accession # | [BBS7], Gene ID: 55212, NCBI: NP_060660.2, UniProt: Q8IWZ6 |
| Catalog # | MBS9603477 |
| Price | $240, $280 |
| Order / More Info | BBS7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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