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Antigenic Specificity | WAC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway. |
Immunogen | Immunogen: Recombinant human WW domain-containing adapter protein with coiled-coil protein |
Other Names | [WW domain-containing adapter protein with coiled-coil; WAC; KIAA1844] |
Gene, Accession # | [WAC], Gene ID: 51322, NCBI: NP_057712.2, UniProt: Q9BTA9 |
Catalog # | MBS7043831 |
Price | $160, $235 |
Order / More Info | WAC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |