Phospho-FoxO1 (Ser319) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-FoxO1 (Ser319)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB); Immunohistochemistry (IHC); ELISA (EIA)
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DescriptionPolyclonal antibody to detect FoxO1 (Phospho-Ser319) in human; mouse and Rat samples. Forkhead box O (FoxO) transcription factors are downstream targets of the serine/threonine protein kinase B (PKB) /Akt. The Akt kinase regulates processes of cellular proliferation and survival. Within the family; three members (FoxO1; FoxO4; and FoxO3a) have sequence similarity to the nematode orthologue DAF-16; which mediates signaling via a pathway involving IGFR1; PI3K; and Akt. The FoxO signaling is regulated by their interactions with other intracellular proteins as well as their post-translational modifications such as phosphorylation. Increased proliferation results when forkhead transcription factors are inactivated through phosphorylation by Akt
ImmunogenImmunogen: Synthesized peptide derived from human FoxO1 around the phosphorylation site of S319
Other Names[FOXO1; FKHR; FOXO1A; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma], [FOXO1; FOXO1; FKH1; FKHR; FOXO1A; FKHR; FOXO1A]
Gene, Accession #[FoxO1], Gene ID: 2308, NCBI: NP_002006.2, UniProt: Q12778
Catalog #MBS845896
Price$335
Order / More InfoPhospho-FoxO1 (Ser319) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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