Edit |   |
Antigenic Specificity | Mouse Dapk3 (Center), 255-282 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of mouse Dapk3. Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By simi |
Immunogen | n/a |
Other Names | [Death-associated protein kinase 3; DAP kinase 3; DAP-like kinase; Dlk; MYPT1 kinase; ZIP-kinase; Dapk3; Zipk] |
Gene, Accession # | [Dapk3], Gene ID: 13144, NCBI: NP_001177402.1, UniProt: O54784 |
Catalog # | MBS9204223 |
Price | $165, $370 |
Order / More Info | Mouse Dapk3 (Center), 255-282 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chang, A.N., et al. J. Biol. Chem. 285(8):5122-5126(2010) Ohbayashi, N., et al. Biochem. Biophys. Res. Commun. 372(4):708-712(2008) Wooldridge, A.A., et al. J. Biol. Chem. 283(17):11850-11859(2008) Shoval, Y., et al. PLoS Genet. 3(10):1884-1893(2007) Sato, N., et al. Int. Immunol. 17(12):1543-1552(2005) |