Phospho-NF kappaB p65 (Ser536) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-NF kappaB p65 (Ser536) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-NF-kappaB p65 (Ser536) antibody detects endogenous levels of NF-kappaB p65 only when phosphorylated at Serine 536. Description: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.Function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as infl |
| Immunogen | Immunogen: A synthesized peptide derived from human NF-kappaB p65 around the phosphorylation site of Serine 536 Subcellular Location: Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalized with RELA in the nucleus upon TNF-alpha induction. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (91%), Horse (91%), Sheep (91%), Dog (100%) |
| Other Names | [Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65; p65 NF kappaB; p65 NFkB; relA; TF65_HUMAN; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V rel avian reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65] |
| Gene, Accession # | [RELA], Gene ID: 5970, NCBI: NP_001138610.1, UniProt: Q04206 |
| Catalog # | MBS9600624 |
| Price | $240, $280 |
| Order / More Info | Phospho-NF kappaB p65 (Ser536) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li C, Zhao B, Lin C, Gong Z, An X; Journal: Cell Biol Int. TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-kB signaling. Zhu L, Xu H, Lv W, He Z, Ye P, Wang Y, Hu J; Journal: Inflammation. miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3beta and NF-kB Pathways. Yang Z, Zheng B, Zhang Y, He M, Zhang XH, Ma D, Zhang RN, Wu XL, Wen JK; Journal: Biochim Biophys Acta. miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells. Minfei Yang, Bing Liu, Libin Jin, Huimin Tao, Zhengming Yang; Journal: Journal of Bone Oncology. Estrogen receptor beta exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NFkB/BCL-2 and PI3K/Akt signal pathway. Ding W, Shen Y, Li Q, Jiang S, Shen H; Journal: Life Sci. Therapeutic mild hypothermia improves early outcomes in rats subjected to severe sepsis. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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