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Antigenic Specificity | CK19 / CYFRA21-1 (Capture Ab) |
Clone | [D5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Chemilumineseent immunoassay (CLIA). Other applications have not been tested. The optimal dilutions should not be determined by end user. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It specifically recognize the human CK19 / CYFRA21-1, and may cross react with CK20, CK8 & CK18. Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. KRT19 is also known as Cyfra 21-1. The usefulness of serum CYFRA 21-1 (cytokeratin-19 fragments) in monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 may be a reliable marker of recurrence or therapeutic efficacy. The serum level of Cyfra21-1 was a useful biomarker for diagnosis of nonsmall cell lung cancer (NSCLC) as well. The serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can |
Immunogen | Immunogen: 40 KDa of Keratin 19 protein. |
Other Names | n/a |
Gene, Accession # | [CK19 / CYFRA21-1] |
Catalog # | MBS355710 |
Price | $535 |
Order / More Info | CK19 / CYFRA21-1 (Capture Ab) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). New consensus nomenclature for mammalian keratins. J Cell Biol 174 (2): 169-74.2. Nakata B, Takashima T, Ogawa Y, Ishikawa T, Hirakawa K. Serum CYFRA 21-1 (cytokeratin-19 fragments) is a useful tumour marker for detecting disease relapse and assessing treatment efficacy in breast cancer. Br J Cancer. 2004 Aug 31;91(5):873-8.3. Cui C, Sun X, Zhang J, Han D, Gu J. The value of serum Cyfra21-1 as a biomarker in the diagnosis of patients with non-small cell lung cancer: a meta-analysis. J Cancer Res Ther. 2014 Nov;10 Suppl:C131-4.4. Song XM, Wang SZ, Wang ZJ, Cao WJ, L J, Chen F. Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma. Neoplasma. 2015;62(1):124-9. |