CK19 / CYFRA21-1 (Capture Ab) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCK19 / CYFRA21-1 (Capture Ab)
Clone[D5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA), Chemilumineseent immunoassay (CLIA). Other applications have not been tested. The optimal dilutions should not be determined by end user.
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DescriptionSpecificity: It specifically recognize the human CK19 / CYFRA21-1, and may cross react with CK20, CK8 & CK18. Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. KRT19 is also known as Cyfra 21-1. The usefulness of serum CYFRA 21-1 (cytokeratin-19 fragments) in monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 may be a reliable marker of recurrence or therapeutic efficacy. The serum level of Cyfra21-1 was a useful biomarker for diagnosis of nonsmall cell lung cancer (NSCLC) as well. The serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can
ImmunogenImmunogen: 40 KDa of Keratin 19 protein.
Other Namesn/a
Gene, Accession #[CK19 / CYFRA21-1]
Catalog #MBS355710
Price$535
Order / More InfoCK19 / CYFRA21-1 (Capture Ab) Antibody from MYBIOSOURCE INC.
Product Specific References1. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). New consensus nomenclature for mammalian keratins. J Cell Biol 174 (2): 169-74.2. Nakata B, Takashima T, Ogawa Y, Ishikawa T, Hirakawa K. Serum CYFRA 21-1 (cytokeratin-19 fragments) is a useful tumour marker for detecting disease relapse and assessing treatment efficacy in breast cancer. Br J Cancer. 2004 Aug 31;91(5):873-8.3. Cui C, Sun X, Zhang J, Han D, Gu J. The value of serum Cyfra21-1 as a biomarker in the diagnosis of patients with non-small cell lung cancer: a meta-analysis. J Cancer Res Ther. 2014 Nov;10 Suppl:C131-4.4. Song XM, Wang SZ, Wang ZJ, Cao WJ, L J, Chen F. Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma. Neoplasma. 2015;62(1):124-9.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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