Phospho-Claudin 7 (Tyr210) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Claudin 7 (Tyr210)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: phospho-Claudin 7 (Tyr210) antibody detects endogenous levels of phospho-Claudin 7 only when phosphorylated at Tyr210. Description: Plays a major role in tight junction-specific obliteration of the intercellular space.Post Translational Modifications: Phosphorylated.Subunit Structure: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity). The phosphorylated form interacts with EPCAM (PubMed:16054130). Does not interact with CD81 (PubMed:20375010).Similarity: Belongs to the claudin family.
ImmunogenImmunogen: A synthesized peptide derived from human phospho-Claudin 7 around the phosphorylation site of Tyr210. Tissue Specificity: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of ex
Other Names[CEPTR L2; CEPTRL 2; CEPTRL2; Claudin 1; Claudin 9; Claudin-7; Claudin1; Claudin7; Claudin9; CLD7_HUMAN; CLDN 7; CLDN-7; Clostridium perfringens enterotoxin receptor like 2; CPETR L2; CPETRL 2; CPETRL2; Hs.84359]
Gene, Accession #[CLDN7], Gene ID: 1366, NCBI: NP_001171951.1, UniProt: O95471
Catalog #MBS9610815
Price$225, $280, $340
Order / More InfoPhospho-Claudin 7 (Tyr210) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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