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Antigenic Specificity | FGFR1/2 (Phospho-Tyr463/466) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenes |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 463/466(S-E-Y(p)-E-L) derived from Human FGFR1/2. |
Other Names | [BFGFR; CEK; FLG; CD331; FLT2] |
Gene, Accession # | [FGFR1/2], Gene ID: 2260, NCBI: NP_001167534.1, UniProt: P11362 |
Catalog # | MBS9405896 |
Price | $200, $255 |
Order / More Info | FGFR1/2 (Phospho-Tyr463/466) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |