Edit |   |
---|---|
Antigenic Specificity | EIF4EBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity. |
Immunogen | Immunogen: A synthesized peptide derived from human eIF4EBP1 |
Other Names | [4E-BP1; 4EBP1; BP-1; MGC4316; PHAS-I] |
Gene, Accession # | [EIF4EBP1], Gene ID: 1978, NCBI: NP_004086.1, UniProt: Q13541 |
Catalog # | MBS8543032 |
Price | $280 |
Order / More Info | EIF4EBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |