CASP2, 432-461 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CASP2, 432-461 |
| Clone | [550CT8.5.2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CASP2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 432-461 amino acids from human CASP2. This gene encodes a member of the cysteine-aspartic acidprotease (caspase) family. Sequential activation of caspases playsa central role in the execution-phase of cell apoptosis. Caspasesexist as inactive proenzymes composed of a prodomain, a largeprotease subunit, and a small protease subunit. Activation ofcaspases requires proteolytic processing at conserved internalaspartic residues to generate a heterodimeric enzyme consisting ofthe large and small subunits. This protein is involved in theprogrammed cell death induced by Fas and various apoptotic stimuli.The N-term |
| Immunogen | n/a |
| Other Names | [Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; Caspase-8 subunit p18; Caspase-8 subunit p10; CASP8; MCH5] |
| Gene, Accession # | [CASP8], Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
| Catalog # | MBS9200315 |
| Price | $370 |
| Order / More Info | CASP2, 432-461 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wurstle, M.L., et al. J. Biol. Chem. 285(43):33209-33218(2010) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Kesarwani, P., et al. BJU Int. (2010) In press : Lee, S.Y., et al. J Thorac Oncol 5(8):1152-1158(2010) Elrod, H.A., et al. PLoS ONE 5 (8), E12178 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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