EBI3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEBI3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionEBI3 Antibody: EBI3 is a subunit in two distinct heterodimeric cytokines: interleukin-27 (IL-27) and IL-35. Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 (also known as TCCR) and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used
ImmunogenImmunogen: EBI3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human EBI3. Buffer: EBI3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[EBI3; IL27B; IL-27B; IL27B; Interleukin-27 subunit beta; Epstein-Barr virus-induced gene 3 protein; IL-27 subunit beta; Epstein-Barr virus induced 3], [EBI3; EBI3; IL27B; IL-27B; IL27B; IL-27 subunit beta; IL-27B; EBV-induced gene 3 protein]
Gene, Accession #[EBI3], Gene ID: 10148, NCBI: NP_005746, UniProt: Q14213
Catalog #MBS150710
Price$375
Order / More InfoEBI3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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