EHMT2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEHMT2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionHistone methyltransferase that specifically mono-and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 877-1176 of human EHMT2 (NP 079532.5).
Other Names[G9A; BAT8; GAT8; NG36; KMT1C; C6orf30]
Gene, Accession #[EHMT2], Gene ID: 10919, NCBI: Q96KQ7.3, UniProt: Q96KQ7
Catalog #MBS8544343
Price$280
Order / More InfoEHMT2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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