Cardiotin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCardiotin
Clone[SR-3]
Host SpeciesMouse
Reactive Specieshuman, porcine
IsotypeIgM
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) (frozen), Western Blot (WB)
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DescriptionSpecificity: SR-3 reacts with cardiotin, a mitochondrion-associated protein, which is present in cardiomyocytes and skeletal muscle, but also in epithelial cells and tissues. Cardiotin is a high molecular weight protein complex (300 kDa) loCated in the mitochondria of cardiomyocytes and skeletal muscle. The cardiotin structure exists of subunits of 60 kDa and 100 kDa, probably in a tetrameric configuRation. Both subunits contain the same amino-terminal 14 amino-acid sequence, showing high homology to Human skeletal muscle alpha-actinin. During cardiac contractile dysfunction and myocard cell differentiation, the cardiotin distribution is affected. Compared to other structural proteins, cardiotin is one of the first to respond to insults (is
ImmunogenSource Note: SR-3 is a Mouse monoclonal IgM antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with the 100 kDa cardiotin subunit.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS570050
Price$415
Order / More InfoCardiotin Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchaart, G., Moens, L., Endert, J. M., and Ramaekers, F. C. (1997). Biochemical characterization of cardiotin, a sarcoplasmic reticulum associated protein, FEBS Lett 403, 168-72.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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