E-Cadherin (C-terminal fragment) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | E-Cadherin (C-terminal fragment) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Clone M533 was purified by Protein G affinity purification. The E-cadherin antibody detects a 120 kDa* protein corresponding to endogenous E-Cadherin expressed in human A431 cells. Cadherins are transmembrane glycoproteins vital in calcium-dependent cell-cell adhesion during tissue differentiation. Cadherins cluster to form foci of homophilic binding units. A key determinant to the strength of the cadherin-mediated adhesion may be by the juxtamembrane region in cadherins. This region induces clustering and also binds to the protein p120 catenin. The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly t |
| Immunogen | Immunogen: Clone (M533) was generated from a mouse recombinant E-Cadherin protein containing amino acids in the C-terminal region. This sequence is highly conserved in human and rat E-cadherin. |
| Other Names | [Uvomorulin; Cadherin-1; CTF1; CTF2; CTF3; CD324; Epithelial Cadherin], [Cdh1; Cdh1; Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649; E-cadherin] |
| Gene, Accession # | Gene ID: 12550, NCBI: P09803.1, UniProt: P09803 |
| Catalog # | MBS474093 |
| Price | $325 |
| Order / More Info | E-Cadherin (C-terminal fragment) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Takeichi, M. (1988) Development 102:639.Xu, Y. et al. (1997) J. Biol. Chem. 272(21):13463.Qi, J. et al. (2006) Mol. Biol. Cell 17(3):1261. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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