notch1a Antibody from MYBIOSOURCE INC.

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Antigenic Specificitynotch1a
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieszebrafish
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionFunctions as a receptor for membrane-bound ligands jagged1, jagged2 and delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER a
ImmunogenImmunogen: Recombinant Zebrafish Neurogenic locus notch homolog protein 1 protein (21-338AA)
Other Names[Neurogenic locus notch homolog protein 1; Notch 1; Notch 1 extracellular truncation; NEXT; Notch 1 intracellular domain; NICD; notch1a; notch]
Gene, Accession #[notch1a], Gene ID: 30718, NCBI: NP_571516.1, UniProt: P46530
Catalog #MBS7104358
Price$160, $235
Order / More Infonotch1a Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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