TPH2 (Phospho-Ser19) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTPH2 (Phospho-Ser19)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of TPH2 only when phosphorylated at serine 19. This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.Walther D.J., Science 299:76-76(2003).Scherer S.E., Nature 440:346-351(2006).
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 19(G-F-S(p)-L-D) derived from Human TPH2.
Other Names[ADHD7; NTPH; TPH2]
Gene, Accession #[TPH2], Gene ID: 121278, NCBI: NP_775489.2, UniProt: Q8IWU9
Catalog #MBS9409804
Price$200, $255
Order / More InfoTPH2 (Phospho-Ser19) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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