Mouse CD104 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD104
Clone[346-11A]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a kappa
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsImmunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot
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DescriptionSpecificity: Integrin beta 4 chain (CD104), Mr 200 kDa. CD104 represents the integrin beta 4 subunit that associates non-covalently with integrin alpha 6 (CD49f) to form the alpha 6 beta 4 integrin heterodimer.2, 3 The alpha 6 beta 4 complex is expressed on the basal surface of a variety of epithelial cell types, particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes, and has been found to be associated with a number of malignant tissues.3-5, 6 Hemidesmosomal alpha 6 beta 4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments.7 It is not known if the
ImmunogenImmunogen: Tumor-associated antigen TSP-180 immunoaffinity purified from a transplantable BALB/c mouse lung cell carcinoma.^1
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS673614
Price$285
Order / More InfoMouse CD104 Antibody from MYBIOSOURCE INC.
Product Specific References1. Kennel, S.J., L.J. Foote, and K.M. Flynn. 1986. Cancer Res. 46:707.2. Kennel, S.J., L.J. Foote, R. Falcioni, A. Sonnenberg, C.D. Stringer, C. Crouse, and M.E. Hemler. 1989. J. Biol. Chem. 264:15515.3. Kennel, S.J., V. Godfrey, L.Y. Ch'ang, T.K. Lankford, L.J. Foote, and A Makkinje. 1992. J. Cell. Sci. 101:145.4. Sonnenberg, A., C.J.T. Linders, J.H. Daams, and S.J. Kennel. 1990. J. Cell. Science 96:207.5. Wadsworth, S., M.J. Halvorson, and J.E. Coligan. 1992. J. Immunol. 149:421.6. Constantini, R.M., R. Falcioni, P. Battista, G. Zupi, S.J. Kennel, A., Colassante, I. Venturo, C.G. Curcio, and A. Sacchi. 1990. Cancer Res. 50:6107.7. Sonnenberg, A., J. Calafat, H. Janssen, H. Daams, L.M.H. vander Raaij-Helmer, R. Falcioni, S.J. Kennel, J.D. Aplin, J. Baker, M. Loizdou, and D. Garrod. 1991. J. Cell. Biol. 113:907.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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