FLII Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FLII |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: FLII antibody detects endogenous levels of total FLII. Function: May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.Subunit Structure: Interacts with actin, ACTL6A, NCOA2, CARM1 and MYD88. Interacts with LRRFIP1 and LRRFIP2. Upon LPS stimulation, LRRFIP2 competes for MYD88-binding. LRRFIP1 constitutively blocks the interaction with MyD88, even in the absence of LPS. Interact |
| Immunogen | Immunogen: A synthesized peptide derived from human FLII Subcellular Location: Nucleus. Cytoplasm > Cytoskeleton. Cytoplasm > Cytoskeleton > Centrosome. Colocalizes to actin-rich structures in blastocysts and, together with HRAS1, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes. Tissue Specificity: Strongest expression in skeletal muscle with high expression also in the heart and lung. |
| Other Names | [Fli 1; FLI; Fli1; Flightless 1; Flightless I (Drosophila) homolog; Flightless I homolog; Flightless I homolog (Drosophila); Flightless1; FlightlessI; fliI; FLII_HUMAN; Fliih; FLIL; MGC39265; Protein flightless 1 homolog; Protein flightless-1 homolog] |
| Gene, Accession # | [FLII], Gene ID: 2314, NCBI: NP_001243193.1, UniProt: Q13045 |
| Catalog # | MBS9608492 |
| Price | $240, $280 |
| Order / More Info | FLII Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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