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Antigenic Specificity | TNFAIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFAIP3 antibody detects endogenous levels of total TNFAIP3. Description: A20, also referred to as TNF-alpha-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kappaB (1, 2). It was first identified as a TNF-alpha inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790-amino acid protein containing seven Cys2/Cys2-zinc finger motifs (3). Constitutive expression of A20 is observed in lymphoid tissues (4), but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-alpha (3, 5), IL-1 (3, 5), phorbol esters (6), and LPS (7). Expression of A20 can confer resistance to apoptosis and NF-kappa |
Immunogen | Immunogen: A synthesized peptide derived from human TNFAIP3 Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: By TNF. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (90%), Bovine (82%), Horse (82%), Rabbit (82%), Dog (82%) |
Other Names | [A20; AISBL; MGC104522; MGC138687; MGC138688; OTU domain containing protein 7C; OTU domain-containing protein 7C; OTUD7C; Putative DNA binding protein A20; Putative DNA-binding protein A20; TNAP3_HUMAN; TNF alpha-induced protein 3; TNFA1P2; TNFAIP 3; TNFAIP3 (A20); TNFAIP3; Tumor necrosis factor alpha induced protein 3; Tumor necrosis factor alpha-induced protein 3; Tumor necrosis factor induced protein 3; Tumor necrosis factor inducible protein A20; tumor necrosis factor, alpha-induced protein 3; Zinc finger protein A20] |
Gene, Accession # | [TNFAIP3], Gene ID: 7128, NCBI: NP_001257436.1, UniProt: P21580 |
Catalog # | MBS9607503 |
Price | $240, $280 |
Order / More Info | TNFAIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |