GSK3 beta Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GSK3 beta |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.6 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity Purified Glycogen Synthase Kinase-3 beta Antibody. Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human GSK3 beta protein. Immunoglobulin: IgY. Expression: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain. |
| Other Names | [Glycogen Synthase Kinase 3 Beta; GSK 3 beta; Serine/threonine-protein kinase GSK3B], [GSK3B; GSK3B; GSK-3 beta] |
| Gene, Accession # | [GSK3], Gene ID: 2932, NCBI: P49841.2, UniProt: P49841 |
| Catalog # | MBS541779 |
| Price | $390 |
| Order / More Info | GSK3 beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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