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Antigenic Specificity | Fibrillin |
Clone | [11C1.3] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.2 mg |
Concentration | n/a |
Applications | Immunofluorescence; Immunohistochemistry; Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human and bovine fibrillin (Mr 350 kDa); other species not tested. The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.^1 In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture |
Immunogen | Immunogen: Microfibrils from zonular apparatus of bovine eye |
Other Names | [Mouse Fibrillin - Purified, Unlabeled; Mouse Fibrillin], [tlr0419] |
Gene, Accession # | Gene ID: 1012664, NCBI: NP_681209.1 |
Catalog # | MBS673084 |
Price | $340 |
Order / More Info | Fibrillin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Sakai, L.Y., et al. 1986. J. Cell. Biol. 103:2499.2. Maier, A., et al. 1994. Investigative Opthamology and Visual Science 35:3103.3. Wright, D.W., et al. 1994. Matrix Biol. 14:41.4. Godfrey, M., et al. 1995. J. Amer. Acad. Dermatol. 56:1287. |