Edit |   |
---|---|
Antigenic Specificity | HTR2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:8882600, PubMed:18703043, PubMed:23519210). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:12970106, PubMed:18703043, PubMed:23519210, PubMed:23519215, PubMed:24357322, PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:8143856, PubMed:8078486, PubMed:8882600, PubMed:23519215, PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activati |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP 000858.3). |
Other Names | [5-HT2B; 5-HT-2B; 5-HT(2B)] |
Gene, Accession # | [HTR2B], Gene ID: 3357, NCBI: NP_000858.3, UniProt: P41595 |
Catalog # | MBS8545707 |
Price | $280 |
Order / More Info | HTR2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |