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Antigenic Specificity | Toll interacting protein (TOLLIP/TOLIP) ((CT)) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules to activate various kinases and transcription factors (3) so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation (4). This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and |
Immunogen | Immunogen: Rabbit polyclonal TOLLIP antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human TOLLIP. |
Other Names | [TOLLIP (CT): Toll interacting protein], [TOLLIP; TOLLIP; IL-1RAcPIP] |
Gene, Accession # | [TOLLIP/TOLIP], Gene ID: 54472, NCBI: NP_061882.2, UniProt: Q9H0E2 |
Catalog # | MBS395528 |
Price | $405 |
Order / More Info | Toll interacting protein (TOLLIP/TOLIP) ((CT)) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |