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Antigenic Specificity | Htr2a (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Htr2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human Htr2a. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phosph |
Immunogen | n/a |
Other Names | [5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A; Htr2a; Htr2] |
Gene, Accession # | [Htr2a], Gene ID: 15558, NCBI: NP_766400.1, UniProt: P35363 |
Catalog # | MBS9209693 |
Price | $165, $370 |
Order / More Info | Htr2a (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yang W.,et al.J. Neurosci. Res. 33:196-204(1992). Fiorica-Howells E.,et al.Am. J. Physiol. 282:G877-G893(2002). Becamel C.,et al.J. Biol. Chem. 279:20257-20266(2004). Weisstaub N.V.,et al.Science 313:536-540(2006). Gonzalez-Maeso J.,et al.Neuron 53:439-452(2007). |