Human CLPX Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CLPX
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatDyLight 488 conjugate
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionSpecificity: No cross reactivity with other proteins. ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, o
ImmunogenImmunogen: E Coli-derived human CLPX recombinant protein (Position: A337-E574).
Other Names[Rabbit IgG Human CLPX DyLight 488 Conjugated, Flow Validated; ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; CLPX; Caseinolytic mitochondrial matrix peptidase chaperone subunit]
Gene, Accession #[CLPX], Gene ID: 10845, NCBI: NP_006651.2, UniProt: O76031
Catalog #MBS1751294
Price$330
Order / More InfoHuman CLPX Antibody from MYBIOSOURCE INC.
Product Specific References1. Corydon, T. J., Wilsbech, M., Jespersgaard, C., Andresen, B. S., Borglum, A. D., Pedersen, S., Bolund, L., Gregersen, N., Bross, P. Human and mouse mitochondrial orthologs of bacterialClpX. Mammalian Genome 11: 899-905, 2000. 2. Kang, S. G., Dimitrova, M. N., Ortega, J., Ginsburg, A., Maurizi, M. R. Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J. Biol. Chem. 280: 35424-35432, 2005.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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