Edit |   |
---|---|
Antigenic Specificity | RSPO-3 (R-Spondin 3, Cristin-1) |
Clone | [7H222] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse RSPO-3. No crossreactivity with recombinant mouse RSPO-1, RSPO-4, recombinant human RSPO-2 or RSPO-3. RSPO-3 (R-spondin 3; also Cristin-1), is a 256aa secreted R-Spondin family member which binds LRP-6 and Fzd8 and regulates b-catenin signaling. R-Spondins contain two adjacent cysteine-rich furin-like domains at their amino-termini, followed by a thrombospondin (TSP-1) motif and a variable length basic C-terminal region. Two RSPO-3 splice isoforms that differ in their C-termini have been reported. Mouse RSPO-3 shares 93% and 97% aa identity with human and rat RSPO-3, respectively, over the sequence used as an immunogen. |
Immunogen | Immunogen: Recombinant corresponding to aa21-209 of mouse RSPO-3 expressed in E. coli (Accession #BAC36296). |
Other Names | [-RSPO-3 (R-Spondin 3, Cristin-1)], [RSPO1; RSPO1; RSPO; CRISTIN3; RP11-566C13.1; hRspo1] |
Gene, Accession # | Gene ID: 284654, NCBI: NP_001229839.1, UniProt: Q2MKA7 |
Catalog # | MBS603109 |
Price | $655 |
Order / More Info | RSPO-3 (R-Spondin 3, Cristin-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |