Caspase-9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-9
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects 45 kDa procaspase-9, 35/37 kDa cleaved immediate fragments and the 17-25 kDa fully cleaved caspase-9. Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. The complex processes procaspase-9 into a large subunit (35 kDa or 17-25 kDa) and small (10 kDa) by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo b
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 290 of mouse caspase-9
Other Names[CASP-9,EC 3.4.22.62,ICE-like apoptotic protease 6; ICE-LAP6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3; Apaf-3], [Casp9; Casp9; Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9; Mch6; CASP-9; APAF-3; ICE-LAP6]
Gene, Accession #Gene ID: 12371, NCBI: BAA86895
Catalog #MBS840560
Price$150, $300
Order / More InfoCaspase-9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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