Edit |   |
---|---|
Antigenic Specificity | CTNND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CTNND1 antibody detects endogenous levels of total CTNND1. Description: Catenin delta-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function (1). Catenin delta-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion (2). Catenin delta-1 has both positive and negative effects on cadherin-mediated adhesion (3). Actin dynamics are also regulated by catenin delta-1, which modulates RhoA, Rac, and cdc42 |
Immunogen | Immunogen: A synthesized peptide derived from human CTNND1 Subcellular Location: Cytoplasm. Nucleus. Cell Membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm. Tissue Specificity: Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in no |
Other Names | [Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN] |
Gene, Accession # | [CTNND1], Gene ID: 1500, NCBI: NP_001078927.1, UniProt: O60716 |
Catalog # | MBS9607180 |
Price | $240, $280 |
Order / More Info | CTNND1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |