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Antigenic Specificity | NOTCH3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of human colon cancer tissue lysate, using NOTCH3 antibody. Immunohistochemistry of paraffin-embedded human colon cancer tissue using NOTCH3 antibody. Notch proteins (Notch1-4) are a family of transmembrane receptors that play important roles in development and the determination of cell fate (1). Mature Notch receptors are processed and assembled as heterodimeric proteins, with each dimer comprised of a large extracellular ligand-binding domain, a single-pass transmembrane domain, and a smaller cytoplasmic subunit (Notch intracellular domain, NICD) (2). Binding of Notch receptors to ligands of the Delta-Serrate-Lag2 (DSL) family triggers heterodimer dissociation, exposing the receptors to prote |
Immunogen | Immunogen: A synthetic peptide of human NOTCH3 |
Other Names | n/a |
Gene, Accession # | [NOTCH3] |
Catalog # | MBS4150250 |
Price | $385 |
Order / More Info | NOTCH3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |