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Antigenic Specificity | Smad6 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Smad6. It was validated on Western BlotTarget Description: Smad6 binds to regulatory elements in target promoter regions. It may block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. It acts as a mediator of TGF-beta and BMP antiflammatory activity. It suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Smad6 |
Other Names | [mothers against decapentaplegic homolog 6; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic homolog 6; SMAD family member 6; Mad homolog 7; SMAD family member 6; SMAD 6; Smad6] |
Gene, Accession # | [SMAD6], Gene ID: 17130, NCBI: NP_032568.3, UniProt: O35182 |
Catalog # | MBS3201101 |
Price | $335 |
Order / More Info | Smad6 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |