CHP2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CHP2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CHP2 antibody detects endogenous levels of total CHP2. Function: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.Subunit Structure: Interacts with PPP3CA. Interacts with SLC9A1/NHE1; the interaction occurs in a calcium- |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Plasma Membrane; Nucleus Tissue Specificity: Expressed in malignantly transformed cells but not detected in normal tissues. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit Similarity: Pig (100%), Zebrafish (80%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%) |
| Other Names | [Calcineurin B homologous protein 2; HCA520; Hepatocellular carcinoma associated antigen 520] |
| Gene, Accession # | [CHP2], Gene ID: 63928, NCBI: NP_071380.1, UniProt: O43745 |
| Catalog # | MBS9605316 |
| Price | $240, $280 |
| Order / More Info | CHP2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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