XIAP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | XIAP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP (XIAP) detection. Background: XIAP, also known as IAP3 or BIRC4, is a protein that stops apoptotic cell death. It is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death prot |
| Immunogen | Immunogen: E Coli-derived human XIAP recombinant protein (Position: A15-V244). Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP, respectively. |
| Other Names | [API3; Api3; Birc4; API 3; BIRC4; IAP3; BIRC 4; E3 ubiquitin-protein ligase XIAP; hIAP3; hIAP-3; HILP; IAP 3; IAP-like protein; ILP 1; X linked IAP; X-linked IAP; X-linked inhibitor of apoptosis; XLP2; P98170; E3 ubiquitin-protein ligase XIAP; X-linked inhibitor of apoptosis], [XIAP; XIAP; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; API3; BIRC4; IAP3; ILP; hILP; IAP-3; hIAP-3; hIAP3; X-linked IAP] |
| Gene, Accession # | [XIAP], Gene ID: 331, NCBI: NP_001158.2, UniProt: P98170 |
| Catalog # | MBS178465 |
| Price | $280 |
| Order / More Info | XIAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cummins, J. M., Kohli, M., Rago, C., Kinzler, K. W., Vogelstein, B., Bunz, F.X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells.Cancer Res. 64: 3006-3008, 2004.2. Deveraux, Q. L., Takahashi, R., Salvesen, G. S., Reed, J. C.X-linked IAP is a direct inhibitor of cell-death proteases.Nature 388: 300-304, 1997.3. Kim, J., Park, J., Choi, S., Chi, S.-G., Mowbray, A. L., Jo, H., Park, H.X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.Circ. Res. 102: 896-904, 2008. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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