Edit |   |
---|---|
Antigenic Specificity | PACS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2. The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4). |
Immunogen | Immunogen: PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. Buffer: PACS1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Phosphofurin acidic cluster sorting protein 1; PACS-1; MRD17; Phosphofurin acidic cluster sorting protein 1], [PACS1; PACS1; MRD17; KIAA1175; PACS-1] |
Gene, Accession # | [PACS1], Gene ID: 55690, NCBI: NP_060496, UniProt: Q6VY07 |
Catalog # | MBS153625 |
Price | $375 |
Order / More Info | PACS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |