PACS1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPACS1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2. The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).
ImmunogenImmunogen: PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. Buffer: PACS1 antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Phosphofurin acidic cluster sorting protein 1; PACS-1; MRD17; Phosphofurin acidic cluster sorting protein 1], [PACS1; PACS1; MRD17; KIAA1175; PACS-1]
Gene, Accession #[PACS1], Gene ID: 55690, NCBI: NP_060496, UniProt: Q6VY07
Catalog #MBS153625
Price$375
Order / More InfoPACS1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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