WEE1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWEE1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for WEE1 detection. Tested with WB in Human; Mouse; Rat.Background: Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). I t is mapped to 11p15.4. This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence of human WEE1 (ELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDR).
Other Names[Wee1-like protein kinase; WEE1hu; Wee1A kinase; WEE1; WEE1 G2 checkpoint kinase]
Gene, Accession #[WEE1], Gene ID: 7465, NCBI: NP_001137448.1, UniProt: P30291
Catalog #MBS1751335
Price$280
Order / More InfoWEE1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Heald, R., McLoughlin, M., McKeon, F. Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase. Cell 74: 463-474, 1993. 2. Igarashi, M., Nagata, A., Jinno, S., Suto, K., Okayama, H. Wee1 ( )-like gene in human cells. Nature 353: 80-83, 1991. 3. Matsuo, T., Yamaguchi, S., Mitsui, S., Emi, A., Shimoda, F., Okamura, H. Control mechanism of the circadian clock for timing of cell division in vivo. Science 302: 255-259, 2003.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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