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Antigenic Specificity | WEE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for WEE1 detection. Tested with WB in Human; Mouse; Rat.Background: Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). I t is mapped to 11p15.4. This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human WEE1 (ELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDR). |
Other Names | [Wee1-like protein kinase; WEE1hu; Wee1A kinase; WEE1; WEE1 G2 checkpoint kinase] |
Gene, Accession # | [WEE1], Gene ID: 7465, NCBI: NP_001137448.1, UniProt: P30291 |
Catalog # | MBS1751335 |
Price | $280 |
Order / More Info | WEE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Heald, R., McLoughlin, M., McKeon, F. Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase. Cell 74: 463-474, 1993. 2. Igarashi, M., Nagata, A., Jinno, S., Suto, K., Okayama, H. Wee1 ( )-like gene in human cells. Nature 353: 80-83, 1991. 3. Matsuo, T., Yamaguchi, S., Mitsui, S., Emi, A., Shimoda, F., Okamura, H. Control mechanism of the circadian clock for timing of cell division in vivo. Science 302: 255-259, 2003. |