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Antigenic Specificity | SHP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SHP2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. |
Immunogen | Immunogen: SHP2 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2 as the immunogen. |
Other Names | [Rabbit SHP2; SHP2; SHP2; PTP-2C; SHP-2; SHP2; Tyrosine-protein phosphatase non-receptor type 11; SHP 2; Phospho Tyr542; SHP 2; PTPN11; Protein-tyrosine phosphatase 2C; SHP-2; PTP-1D; Protein-tyrosine phosphatase 1D] |
Gene, Accession # | [SHP2], NCBI: ACA42768.1 |
Catalog # | MBS5309616 |
Price | $295 |
Order / More Info | SHP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |