GAD2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GAD2 |
| Clone | [6D5-E8-E4] |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG2b |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 4.76mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. UniPort Summary Function: Catalyzes the production of GABA. |
| Immunogen | Immunogen: Purified recombinant human GAD2 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of GAD2 and does not cross-react with related proteins. Sequence Similarities: Belongs to the group II decarboxylase family. |
| Other Names | [65 kDa glutamic acid decarboxylase; DCE 2; DCE2; DCE2_HUMAN; GAD 2; GAD 65; GAD-2; GAD-65; Gad2; Glutamate decarboxylase 2 (pancreas); Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa); Glutamate decarboxylase 2; Glutamate Decarboxylase 65; Glutamate decarboxylase 65 kDa isoform; Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65; MGC161605; MGC161607], [GAD65] |
| Gene, Accession # | [GAD2], Gene ID: 2572, NCBI: NP_000809.1, UniProt: Q05329 |
| Catalog # | MBS475590 |
| Price | $335 |
| Order / More Info | GAD2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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