JAK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJAK2
Clone[6B4-8G2-1C4]
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC)
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DescriptionNon-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins (PubMed:7615558). Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins (PubMed:9618263). Subsequently, phosphorylat
ImmunogenImmunogen: Synthetic peptide conjugated to KLH.
Other Names[Janus kinase 2; JTK10; Tyrosine protein kinase Jak2; THCYT3]
Gene, Accession #[JAK2], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674
Catalog #MBS8539830
Price$280
Order / More InfoJAK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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