Human CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD40
Clone[4A3A8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatphycoerythrin (PE) conjugate
Size50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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Description4A3A8 reacts with CD40 (Bp50), a member of the TNF receptor family with 48 kDa MW. which is expressed on B lymphocytes including pro-B through to plasma cells but not on monocytes nor granulocytes. CD40 also expressed on dendritic cells and CD34+ hemopoietic cell progenitor. CD40 molecule involved in regulation of B-cell growth, differentiation and Isotype-switching of Ig and up-regulates adhesion molecules on dendritic cells as well as promotes cytokine production in macrophages and dendritic cells. CD40 antibodies has been reported to co-stimulate B-cell proleferation with anti-m or phorbol esters. It may be an important target for control of graft rejection, T cells and antibody-mediated autoimmune diseases.
Immunogenn/a
Other Names[CD40, partial; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 molecule; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD_antigen: CD40]
Gene, Accession #[CD40], Gene ID: 958, NCBI: ABI49511.1
Catalog #MBS8500381
Price$280, $300
Order / More InfoHuman CD40 Antibody from MYBIOSOURCE INC.
Product Specific References1. Stamenkovic I et al., (1989) EMBO J. 8:1403.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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