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Antigenic Specificity | PHAX - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentaliz |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHAX |
Other Names | [phosphorylated adapter RNA export protein; Phosphorylated adapter RNA export protein; phosphorylated adapter RNA export protein; phosphorylated adaptor for RNA export; RNA U small nuclear RNA export adapter protein] |
Gene, Accession # | [PHAX], Gene ID: 51808, NCBI: NP_115553.2, UniProt: Q9H814 |
Catalog # | MBS3223338 |
Price | $335 |
Order / More Info | PHAX - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |