RAB7L1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAB7L1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: RAB7L1 antibody detects endogenous levels of total RAB7L1. Function: Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.Subunit Structure: Interacts with LRRK2.Post-translational Modifications: In
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane. Cytoplasm. Cytoplasm, Perinuclear Region. Golgi Apparatus. Golgi Apparatus, Trans-Golgi Network. Vacuole. Cytoplasm, Cytoskeleton. Colocalizes with LRRK2 along tubular structures emerging from golgi apparatus (By similarity). Colocalizes with GM130 at the golgi apparatus. Colocalizes with dynamic tubules emerging from and retracting to the golgi apparatus. Colocalizes with TGN46 at the trans-g``olgi network (TGN). In Salmonell
Other Names[DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab-7-like protein 1; RAB29; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; RAB7L_HUMAN; Ras related protein Rab 7L1; Ras related protein Rab7L1; Ras-related protein Rab-29; Ras-related protein Rab-7L1]
Gene, Accession #[RAB7L1], Gene ID: 8934, NCBI: NP_001129134.1, UniProt: O14966
Catalog #MBS9605863
Price$240, $280
Order / More InfoRAB7L1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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