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Antigenic Specificity | ATG16L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, ratpredicted: human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.Structure: Homooligomer. Interacts with WIPI2, FIP200 and ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Interacts with RAB33B. Interacts with TMEM |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 560-610 on human Autophagy-related protein 16-1. Conjugation: Unconjugated |
Other Names | [Affinity Purified Autophagy-related protein 16-1; APG16 like 1; APG16L; APG16L beta; ATG16 autophagy related 16 like 1; ATG16A; ATG16L; Autophagy related protein 16 1; IBD10; WD repeat domain 30; WDR30] |
Gene, Accession # | [ATG16L1], Gene ID: 55054, NCBI: NP_001177195.1, UniProt: Q676U5 |
Catalog # | MBS5400336 |
Price | $390 |
Order / More Info | ATG16L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |