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Antigenic Specificity | Tollip |
Clone | [k1B17] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity. |
Immunogen | Immunogen: Recombinant human Tollip (61-274aa) purified from E. coli |
Other Names | [Toll interacting protein,IL-1RAcPIP], [TOLLIP; TOLLIP; IL-1RAcPIP] |
Gene, Accession # | [Tollip], Gene ID: 54472, NCBI: NP_061882, UniProt: Q9H0E2 |
Catalog # | MBS200118 |
Price | $240, $315 |
Order / More Info | Tollip Antibody from MYBIOSOURCE INC. |
Product Specific References | Ciarrocchi A. et al., (2009) Published online. 4 (2):e4404; Didierlaurent A. et al., (2006) Mol Cell Biol. 26 (3):735-742; Opal S.M. et al., (2002) Crit Care. 6 (2):125-136; Burns K. et al., (2000) Nat Cell Biol. 2 (6):346-351 |