SPIN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SPIN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SPIN1 antibody detects endogenous levels of total SPIN1. Function: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in ovarian cancer tissues. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [OCR; Ovarian cancer-related protein; SPIN; Spin1; SPIN1_HUMAN; Spindlin-1] |
| Gene, Accession # | [SPIN1], Gene ID: 10927, NCBI: NP_006708.2, UniProt: Q9Y657 |
| Catalog # | MBS9604945 |
| Price | $240, $280 |
| Order / More Info | SPIN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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